"Yes, I remember that severe depression disorder is a very serious mental illness. It is said to be a combination of genetic and environmental factors, and stress is the main environmental risk factor." Linger was also skeptical, and he did not believe in Dr. Lanther Payne's views and treatment at all.

"There is still a principle." Although Zheng Ren does not believe that fecal transplantation can treat major depression, he still tells the truth. "There is increasing evidence that the microbiota is an environmental factor that can shape the brain through the microbiota-gut-brain axis, and mice with changes in the microbial community usually exhibit depression-related behaviors."

"It is said that it is related to the nlrp3 gene." Su Yun added.

"What n?" Linge was stunned.

"Uh..." Zheng Ren found that it was really difficult to explain clearly. He thought for a while and said, "Simply put, it is to make the feces of a mouse knocked out nlrp3... that knocked out some genes related to depression, and then take it orally to the patient."

“…”

Linge and Director Kong were both stunned.

Although I have experienced many battles, I now think of Huanglong Decoction and mouse feces... I feel disgusting when I think about it. Now I still have to take the feces of guinea pigs orally. Can this really cure the disease?

"Director Lin, what's your expression?" Su Yun was very happy and looked at Lin Ge with a serious look, "Do you eat rat shit? It's been there since ancient times."

"I know there is a kind of snack that children eat called rat shit. My friends in Jinling are still looking for it all over the world during festivals. Unfortunately, they are selling less and less."

"The one you are talking about is a snack made from dried tangerine peel, plum, white sugar, and hawthorn." Su Yun laughed and said, "A word reveals his age. What age is this? Who still eats rat shit?"

"Recall, memory."

"Do you know if there is rat shit in Chinese medicine?" Su Yun brought back the topic like a prank.

"Wu Lingzhi, the feces of squirrels with re-toothed teeth." Zheng Ren said, "It is mainly used to treat air conditioning in the heart and abdomen, to cure malnutrition in children, to cure intestinal wind, to clear qi and meridians, and to have a period of confinement in women."

"You're not professional if you say that..."

"Just know the meaning, why do you think so professional?" Zheng Ren said, "The treatment of severe depression by fecal transplant is still in the animal experiment stage, and I am not optimistic about this animal experiment."

"It's because I can't tell whether the guinea pig is really depressed? In fact, it can still be judged through activities, communication, and play." Seeing that Zheng Ren didn't want to say anything, Su Yun smiled and went over and continued to talk about the treatment of depression.

"If you want to treat Clostridium difficile infection, you can try it by using fecal transplantation, but the risk is extremely high." Zheng Ren said, "But..."

"Stop talking nonsense. They are looking for American experts to treat it. Do you believe it or not, just deny it so carelessly. Director Mao's family members drove you out directly?" Su Yun blew, and his black hair was floating on his forehead.

"Not to it."

"What's wrong? I heard that Director Mao is in the onset stage now. No matter who sees him, he will hold his hands and say sorry. His memory is very good, and he will talk about a few small details for a long time." Su Yun said.

"Oh? I think my life is worthless, with extreme guilt, regret, helplessness, and self-abandonment. These points are quite consistent with the major depression disorder." Zheng Ren said: "If this is the case, there is no good idea."

When Lin Ge heard Zheng Ren say this, he lowered his head and sighed.

"Tsk, are you talking about the dsm-iv-tr diagnostic criteria or the icd-10 diagnostic criteria?"

"None are not." Zheng Ren had no idea of ​​quarrel with Su Yun today. He said directly: "I still agree with Director Mei's statement that normal drug treatment. Fecal transplantation, whether it is intestinal or oral capsules, may induce more and bigger problems."

"Okay, I will reflect your views to the yard, Boss Zheng." Lin Ge said cautiously at the end.

"For fecal transplants, there have been many new research findings recently. For example, in a study in the Journal of Cell in August 2019, the Eick Riquelme and Florencia McCallister study at the Anderson Cancer Center in the United States found that the few long-term survival pancreatic cancer patients have significantly more microorganisms in the tumor."

"Can fecal transplantation treat cancer?" Linge was surprised.

"It's just a discovery. Whether it works will take a long time to study it." Zheng Ren said: "It may also be a wrong direction. Fecal transplant is a good thing, but I don't think the means in the experimental stage should be used in clinical practice."

"good."

Lingge nodded, then stood up and said, "Boss Zheng, then I'll report to the yard."

"Director Lin said that Director Mao and her husband confessed, and her husband was angry for an hour, then slammed the door and left. Is there anything wrong?" Su Yun continued gossiping.

Linger smiled bitterly.

"What are you asking so many questions? It doesn't matter if you have diagnosis or treatment." Zheng Ren said.

After hearing what Zheng Ren said, Lin Ge smiled apologetically and turned around and left.

Zheng Ren then said a few words to Director Kong and left the office.

"Boss, do you really think fecal transplantation is unreliable?" Su Yun asked.

"It's not that it's unreliable, but it takes a long time of research. The treatment of C. difficile has been used in clinical practice, but the mortality rate is very high."

"If you don't need it, the mortality rate will be nearly 100%. " Su Yun directly retorted.

"Who knows, the internal medicine treatment method has nothing to do with us." Zheng Ren didn't want to think about these things. Being a surgeon is enough.

"Boss, the subject is involved in the subject, belongs to the imaging major, and is a clinical auxiliary subject." Su Yun was too ungrateful and misinterpreted his meaning, directly hitting Zheng Ren's weakness.

Zheng Ren was too lazy to take care of this guy, so he returned to the office to continue reading.

This time he was looking for information about fecal transplantation.

Fecal transplantation cannot be done in clinical practice without 20 or 30 years.

Zheng Ren just looked at it fresh and didn't want to study it from beginning to end. Even the skill of the Eye of Real has cooled down, so Zheng Ren didn't want to use it.

Who knows how much scope it covers a study? If you use it casually, you may drain your energy and faint.

Zheng Ren suffered a loss once, and he learned to be good at it. The real eye cannot be used casually. The left gastric artery embolization surgery can be seen at a glance. After all, is it simple?

As for fecal transplantation...

As an emerging treatment method, it involves too wide a variety of categories. It seems that it can be found in the treatment of bacterial disorders, depression, cancer, and diabetes.
Chapter completed!